Site Specific Calibration Curve And Its Implication in The Treatment Planning of Head And Neck Cancer.
Keywords:Calibration curve, RANDO phantom, head and neck
Purpose: In this study, we created site specific Hounsfield Unit (HU) and Relative electron density(RED) calibration curves for computed tomography(CT) and cone beam computed tomography (CBCT) for head and neck radiotherapy dose calculation and compared them with standard calibration curves.
The calibration curves between HU and RED were generated using RANDO phantom for CT and CBCT and fed in the treatment planning system for dose calculation for head and neck patients.The treatment plans for 10 head and neck cancer patients were calculated using the standard calibration curves generated with CATPHAN and head and neck calibration curves generated with RANDO phantom for both CT and CBCT. Dose accuracy of head and neck calibration curves(H/N CC) were compared to the standard calibration curves (SCC) using dose volume metrics and 3D gamma analysis.
Results: The results show that slightly better dosimetric agreement from the SCC can be obtained when using this H/N CC.
Conclusions: A site specific calibration curves have been proposed and tested for the head-and-neck patients and the results explain the dosimetric benefits.
W. Parker, H. Patrocinio. “Clinical Treatment Planning in External Photon Beam Radiotherapy.” In: E. B. Podgorsak (Ed.). Radiation Oncology Physics: A Handbook for Teachers and Students. Austria: IAEA, p. 229-273, 2005.
A. Neal. “Patient Data Acquisition.” In: P. Mayles, A. Nahum, J. C. Rosenwald (Org.). Handbook of Radiotherapy Physics: Theory and Practice. Inglaterra: Taylor & Francis, p.647-657, 2007.
A. Barret, J. Dobbs, S. Morris, T. Roques. Practical Radiotherapy Planning. 2009.
Saw CB, Loper A, Komanduri K, Combine T, Huq S, Scicutella C. Determination of CT-to-density conversion relationship for image based treatment planning systems. Med Dosim. 2005;30:145–148.
Cozzi, L.; Fogliata, A.; Buffa, F.; et al. Dosimetric impact of computed tomography calibration on a commercial treatment planning system for external radiation therapy. Radiother. Oncol. 48: 335–8; 1998..
Constantinou, C.; Harrington, J.; Dewerd, L. An electron-density calibration phantom for CT-based treatment planning computers. Med. Phys. 19:325–7; 1992.
Yoo S, Yin FF. Dosimetric feasibility of cone-beam CT-based treatment planning compared to CT-based treatment planning. Int J Radiat Oncol Biol Phys. 2006;66:1553–1561.
Hatton J, McCurdy B, Greer PB. Cone beam computerized tomography: the effect of calibration of the Hounsfield unit number to electron density on dose calculation accuracy for adaptive radiation therapy. Phys Med Biol. 2009;54:N329–N346.
Richter A, Hu Q, Steglich D, et al. Investigation of the usability of cone beam CT data sets for dose calculation. Rad Oncol. 2008;3:42.
James Kwame Annkah, Ivan Rosenberg et al.Assessment of the dosimetric accuracies of CATPhan 504 and CIRS 062 using kV-CBCT for performing direct calculations. J Med Phys. 2014 Jul-Sep; 39(3): 133–141.
Zurl B, Tiefling R, Winkler P, Kindl P, Kapp KS. Hounsfield units variations: Impact on CT-density based conversion tables and their effects on dose distribution. Strahlenther Onkol. 2014;190:88–93.
How to Cite
All articles published in Journal of Advances in Linguistics are licensed under a Creative Commons Attribution 4.0 International License.