Signal-to-Noise Ratio importance in Apparent Diffusion Coefficient measurements using Diffusion-Weighted Echo-Planar-Imaging scans

Authors

  • Cristiano Biagini Centro OncologicoFiorentino, Sesto Fiorentino, Florence(Italy) cristiano.biagini@lacittadellasalute.it
  • Martina De Michele Fisica Sanitaria, University of Florence, Florence (Italy)
  • Andrea Pratesi State Hospital “Misericordia e Dolce”, Prato (Italy)
  • Francesco Mungai Radiodiagnostic Unit n.2, University of Florence, Florence (Italy)
  • Margherita Betti Radiotherapy Unit, Centro Oncologico Fiorentino, Sesto Fiorentino, Florence, Italy
  • Giana Izzo Università Cattolica “Sacro Cuore”, Rome (Italy)
  • Carlo Biagini Centro Oncologico Fiorentino, Sesto Fiorentino, Florence (Italy)
  • Luigi Natale Radiological Sciences and Bioimaging Dept. Catholic University of Sacred Heart

DOI:

https://doi.org/10.24297/jap.v4i2.2034

Keywords:

Diffusion Magnetic Resonance Imaging, Artifacts, MRI Physics, fat suppression techniques.

Abstract

Purpose: To define experimental grounds for Apparent Diffusion Coefficient (ADC) measurements using Spin-Echo Diffusion-Weighted Echo-Planar (SE-DW-EPI) sequences, as a function of Signal-to-Noise Ratio (SNR).

Methods: multiple multi-b SE-DW-EPI scans with the same parameters but the lipid suppression technique have been compared on water phantom with a 3T MRI equipment. The SNR has been estimated using the method of difference. Images have been analyzed manually, comparing the signal intensities at different b-values.

Results: All measurements show a high repeatability and strong self-consistency. A significant dependence of the ADC on SNR has been shown, and its lowest limitto obtain reliable quantitative answers has been stated. Conclusion: ADC measurements in vivo must be carefully designed to avoid systematic errors during acquisition and post-processing due to low SNR.

Downloads

Download data is not yet available.

Author Biographies

Cristiano Biagini, Centro OncologicoFiorentino, Sesto Fiorentino, Florence(Italy) cristiano.biagini@lacittadellasalute.it

Department of Radiology

Francesco Mungai, Radiodiagnostic Unit n.2, University of Florence, Florence (Italy)

Department of Experimental and Clinical Biomedical Sciences

Giana Izzo, Università Cattolica “Sacro Cuore”, Rome (Italy)

Department of Radiological Sciences

Carlo Biagini, Centro Oncologico Fiorentino, Sesto Fiorentino, Florence (Italy)

Department of Radiology

Luigi Natale, Radiological Sciences and Bioimaging Dept. Catholic University of Sacred Heart

Radiological Sciences and Bioimaging Dept.Assistant Professor of Radiology

Downloads

Published

2014-03-28

How to Cite

Biagini, C., De Michele, M., Pratesi, A., Mungai, F., Betti, M., Izzo, G., Biagini, C., & Natale, L. (2014). Signal-to-Noise Ratio importance in Apparent Diffusion Coefficient measurements using Diffusion-Weighted Echo-Planar-Imaging scans. JOURNAL OF ADVANCES IN PHYSICS, 4(2), 517–525. https://doi.org/10.24297/jap.v4i2.2034

Issue

Vol. 4 No. 2

Section

Articles

License

Creative Commons License All articles published in Journal of Advances in Linguistics are licensed under a Creative Commons Attribution 4.0 International License.