A-Alkenoyl Ketene S,S- and N,S-Acetals As Starting For Unexpected and Novel Synthesis of N-Heterocycles

Authors

  • Ahmed M. M. El-Saghier Sohag University, Sohag
  • Mansour A. Makhlouf Tripoli University, Tripoli
  • Naglaa F. H. Mahmoud Ain Shams University, Cairo
  • Wedad A. El-Adawish Al-Zawia University, Al-Zawia

DOI:

https://doi.org/10.24297/jac.v6i1.965

Keywords:

Oxo-ketene Acetals, -Alkenoyl ketene -S, S-acetal,  -Alkenoyl keten-N, Diazaspiro[4.5]decane Pyrazolodiazepine, Pyrazolopyridine

Abstract

A series of N-heterocycles such as diazaspiro-[4.5]decane,  pyrazolo[4,3-d][1,2]-diazepine, imidazo[3,2,1ij][1,8]naphthyridine derivatives or  pyrazolo[3,4-b]pyridin-4-ol were synthesized using a-alkenoyl-, a,a-dialkenoyl ketene-(S,S)-acetals 2a-d, 3a-c or a-dialkenoyl ketene-(N,S)-acetal 12 as starting materials. The biological activity of some new synthesized compounds have been investigated. 

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Author Biographies

  • Ahmed M. M. El-Saghier, Sohag University, Sohag
    Department of Chemistry, Faculty of Science
  • Mansour A. Makhlouf, Tripoli University, Tripoli
    Department of Chemistry, Faculty of Science
  • Naglaa F. H. Mahmoud, Ain Shams University, Cairo
    Department of Chemistry, Faculty of Science
  • Wedad A. El-Adawish, Al-Zawia University, Al-Zawia
    Department of Chemistry, Faculty of Science

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Published

2010-04-10

Issue

Vol. 6 No. 1 (2013)

Section

Articles

License

Creative Commons License All articles published in Journal of Advances in Linguistics are licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

A-Alkenoyl Ketene S,S- and N,S-Acetals As Starting For Unexpected and Novel Synthesis of N-Heterocycles. (2010). JOURNAL OF ADVANCES IN CHEMISTRY, 6(1), 861-872. https://doi.org/10.24297/jac.v6i1.965

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