Synthesis, crystal structure and antifungal activity of dihydroisoquinoline Oxaziridines Substitued in Position 1
DOI:
https://doi.org/10.24297/jac.v10i4.893Keywords:
Oxaziridine, m-CPBA, X-ray diffraction, Antifungal activity.Abstract
We report here the synthesis and the X-ray crystallography of dihydroisoquinoline oxaziridines with methyl substitute in position 1 and with nitro group in position 7 (compound 3b). We also synthesized the compound 3a without nitro. These compounds have been prepared by the peracidic oxidation of imines with m-chloroperbenzoic (m-CPBA) like oxidizing agent. This two compounds exhibit higher antifungal activity.
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Published
2014-05-01
How to Cite
Bouzid, M., Abdennabi, R., Hrizi, C., Gharsallah, N., & Kammoun, M. (2014). Synthesis, crystal structure and antifungal activity of dihydroisoquinoline Oxaziridines Substitued in Position 1. JOURNAL OF ADVANCES IN CHEMISTRY, 10(4), 2551–2557. https://doi.org/10.24297/jac.v10i4.893
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