Synthesis, Characterization and Antitumor Activity of Some New Oganotellurium Compounds Containing Azomethine Group, Part One

Authors

  • Rafid H. Al-Asadi College of Education, University of Basrah
  • Tarik A. Fahad College of Education, University of Basrah
  • Bahjat A. Saeed College of Education, University of Basrah
  • Wasfi A. Al-Masoudi Dept. of Chemistry, College of Education, University of Basrah

DOI:

https://doi.org/10.24297/jac.v8i1.4027

Keywords:

Schiff-base, 3, 4-dihydroxy benzaldehyde, Tellurium tetrabromide, HSQC- NMR, Antitumor

Abstract

New tellurated schiff bases were synthesized by the reaction of the corresponding mercurated Schiff  bases compounds A1-A3 with tellurium tetrabromide in 1:1 mole ratio and  that  gave organyltellurium tribromides  A4-A6.  On the other hand, when mercurated schiff bases and tellurium tetrabromide brought  together in 2:1 mole ratio gave diorganyltellurium dibromides compounds A10-A12 followed by reduction with hydrazine hydrate gave new diorganyl tellurides A13-A15.  Reduction of compounds A4-A6 by  hydrazine hydrate gave new ditellurides A7-A9.  All compounds were characterized by elemental analysis, IR, 1H , 13C NMR, HSQC-NMR and mass spectra.  Invitro anti-tumor bioactivity of some compounds were tested. 

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Author Biographies

  • Rafid H. Al-Asadi, College of Education, University of Basrah
    Dept. of Chemistry
  • Tarik A. Fahad, College of Education, University of Basrah
    Dept. of Chemistry
  • Bahjat A. Saeed, College of Education, University of Basrah
    Dept. of Chemistry
  • Wasfi A. Al-Masoudi, Dept. of Chemistry, College of Education, University of Basrah
    Dr. Wasfi Abboud Al-Masoudi, assistant professor and researcher in the Department of Physiology and Chemistry, Faculty of Vet. Medicine at the University of Basrah, born Basrah - Iraq in 1959, holds a bachelor's, master's and Ph.D. from the Department of Chemistry - Faculty of Education - University of Basrah,Specialization Organicmettalic Chemistry - professor of organic chemistry in the number of Libyan universities and the University of Basrah, published 16 research specialization in a number of international scientific journals also participated by more than a dozen scientific conferences in chemistry with a number of Arab and international countries - published a number of scientific articles and local educational magazines. Awarded several certificates of appreciation for his scientific them a certificate of appreciation from the Union Chemical Arab and African Conference of chemistry.

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Published

2016-12-20

Issue

Vol. 8 No. 1 (2014)

Section

Articles

License

Creative Commons License All articles published in Journal of Advances in Linguistics are licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

Synthesis, Characterization and Antitumor Activity of Some New Oganotellurium Compounds Containing Azomethine Group, Part One. (2016). JOURNAL OF ADVANCES IN CHEMISTRY, 8(1), 1464-1471. https://doi.org/10.24297/jac.v8i1.4027

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