A Facile Synthesis of Pyrimidoquinazoline Derivatives

Authors

  • Mona Boukthir Laboratoire de Chimie Appliquée : Hétérocycles, Corps gras et Polymères à la Faculté des Sciences de Sfax. Route de Soukra Km 3.5. BP 802. Sfax 3000
  • Fathi Zribi Laboratoire de Chimie Appliquée : Hétérocycles, Corps gras et Polymères à la Faculté des Sciences de Sfax. Route de Soukra Km 3.5. BP 802. Sfax 3000
  • Mohamed Belhouchet Laboratoire Physico-Chimie de l’Etat Solide, Faculté des Sciences de Sfax. Route de Soukra Km 3.5. BP 802. Sfax 3000
  • Fakher Chabchoub Laboratoire de Chimie Appliquée : Hétérocycles, Corps gras et Polymères à la Faculté des Sciences de Sfax. Route de Soukra Km 3.5. BP 802. Sfax 3000

DOI:

https://doi.org/10.24297/jac.v7i3.2379

Keywords:

Pyrimidoquinazoline, pyrimidine, X-ray diffraction, Infrared spectroscopy, Nuclear magnetic resonance

Abstract

A series of pyrimidoquinazoline are prepared via the reaction of ethyl 2,2-dicyano-1-arylvinylcarbamate derivatives 1a-b with methyl 2-aminobenzoate, 1-(2-aminophenyl)ethanone and 2-aminobenzonitrile. The reactivity of compounds 1a-b toward 3-amino-4,6-diphénylnicotinonitrile are studied. The structures of the synthesized compounds are elucidated by X-ray diffraction, IR spectroscopy and nuclear magnetic resonance. 

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Published

2011-12-17

How to Cite

Boukthir, M., Zribi, F., Belhouchet, M., & Chabchoub, F. (2011). A Facile Synthesis of Pyrimidoquinazoline Derivatives. JOURNAL OF ADVANCES IN CHEMISTRY, 7(3), 1434-1439. https://doi.org/10.24297/jac.v7i3.2379

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Articles