Synthesis of Fluorinated Pyridines as 19F NMR pH Indicators

Authors

  • Mohammad Ali Amrollahi College of Science, Yazd University, Yazd. Iran, P.O.Box 89195-741

DOI:

https://doi.org/10.24297/jac.v10i3.2275

Keywords:

Fluorination, fluorinated pyridine derivatives, 19F NMR pH indicators, pKa

Abstract

This research was undertaken to synthesizes and evaluate 3,5-dihydroxymethyl-4-(2-fluorophenyl)-2,6-dimethylpyridine and 4-(fluoromethyl)-2,6-dimethylpyridine as indicators of 19F NMR pH. A comparison of 3,5-dihydroxymethyl-4-(2-fluorophenyl)-2,6-dimethylpyridine to 4-(fluoromethyl)-2,6-dimethylpyridine showed that 4-(fluoromethyl)-2,6-dimethylpyridine has a large 19F chemical shift to pH, a suitable pKa value and a good water solubility.

Downloads

Download data is not yet available.

Author Biography

  • Mohammad Ali Amrollahi, College of Science, Yazd University, Yazd. Iran, P.O.Box 89195-741
    Department of Chemistry

Downloads

Published

2014-04-04

Issue

Vol. 10 No. 3 (2014)

Section

Articles

License

Creative Commons License All articles published in Journal of Advances in Linguistics are licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

Synthesis of Fluorinated Pyridines as 19F NMR pH Indicators. (2014). JOURNAL OF ADVANCES IN CHEMISTRY, 10(3), 2441-2446. https://doi.org/10.24297/jac.v10i3.2275

Similar Articles

1-10 of 228

You may also start an advanced similarity search for this article.