Cd-proline Complex Catalyzed Direct one-Pot three Component Mannich Reaction in Water Medium

DOI:

https://doi.org/10.24297/jac.v7i1.970

Keywords:

Cadmium-proline, Metal acetate, Mannich reaction, Water medium

Abstract

Metal-proline complexes of various metals like Zn, Cd, Hg, and Pb were found to be good catalysts for direct Mannich reaction in water medium at room temperature, smoothly affording the β-amino carbonyl compounds in excellent yields. Among the catalyst cadmium-proline complex gave high yield in lesser time. All the catalysts were easily separated from the reaction mixture by water extraction and among this cadmium -proline complex was found to be most stable and can be recycled five times without losing its catalytic activity.

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Published

2011-04-19

How to Cite

Cd-proline Complex Catalyzed Direct one-Pot three Component Mannich Reaction in Water Medium. (2011). JOURNAL OF ADVANCES IN CHEMISTRY, 7(1), 1160–1168. https://doi.org/10.24297/jac.v7i1.970

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Articles