Convenient one-step Synthesis of Substituted Pyrano[2,3-c]isoquinoline (2-amino-4H-chromenes) via three Component Reaction between Alkyl isocyanides and Dialkyl Acetylenedicarboxylate in the presence of 3-Hydroxyisoquinoline

Authors

  • Bita Mohtat Karaj Branch, Islamic Azad University, Karaj
  • Shahla Salmani Karaj Branch, Islamic Azad University, Karaj
  • Amineh Aminian Karaj Branch, Islamic Azad University, Karaj
  • Hoorieh Djahaniani East Tehtan Branch, Islamic Azad University, Tehran

DOI:

https://doi.org/10.24297/jac.v6i1.966

Keywords:

4H-chromenes, alkyl isocyanides, acetylenic ester, 3-hydroxyisoquinoline

Abstract

The reactive intermediate generated by the addition of alkyl isocyanides to dialkyl acetylenedicarboxylate are trapped by 3-hydroxyisoquinoline to produce highly functionalized 4H-chromenes in 83-92% yields.

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Author Biographies

Bita Mohtat, Karaj Branch, Islamic Azad University, Karaj

Chemistry Department

Shahla Salmani, Karaj Branch, Islamic Azad University, Karaj

Chemistry Department

Amineh Aminian, Karaj Branch, Islamic Azad University, Karaj

Chemistry Department

Hoorieh Djahaniani, East Tehtan Branch, Islamic Azad University, Tehran

Chemistry Department

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Published

2010-04-10

How to Cite

Mohtat, B., Salmani, S., Aminian, A., & Djahaniani, H. (2010). Convenient one-step Synthesis of Substituted Pyrano[2,3-c]isoquinoline (2-amino-4H-chromenes) via three Component Reaction between Alkyl isocyanides and Dialkyl Acetylenedicarboxylate in the presence of 3-Hydroxyisoquinoline. JOURNAL OF ADVANCES IN CHEMISTRY, 6(1), 873–877. https://doi.org/10.24297/jac.v6i1.966

Issue

Vol. 6 No. 1 (2013)

Section

Articles

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