A-Alkenoyl Ketene S,S- and N,S-Acetals As Starting For Unexpected and Novel Synthesis of N-Heterocycles

Authors

  • Ahmed M. M. El-Saghier Sohag University, Sohag
  • Mansour A. Makhlouf Tripoli University, Tripoli
  • Naglaa F. H. Mahmoud Ain Shams University, Cairo
  • Wedad A. El-Adawish Al-Zawia University, Al-Zawia

DOI:

https://doi.org/10.24297/jac.v6i1.965

Keywords:

Oxo-ketene Acetals, -Alkenoyl ketene -S, S-acetal,  -Alkenoyl keten-N, Diazaspiro[4.5]decane Pyrazolodiazepine, Pyrazolopyridine

Abstract

A series of N-heterocycles such as diazaspiro-[4.5]decane,  pyrazolo[4,3-d][1,2]-diazepine, imidazo[3,2,1ij][1,8]naphthyridine derivatives or  pyrazolo[3,4-b]pyridin-4-ol were synthesized using a-alkenoyl-, a,a-dialkenoyl ketene-(S,S)-acetals 2a-d, 3a-c or a-dialkenoyl ketene-(N,S)-acetal 12 as starting materials. The biological activity of some new synthesized compounds have been investigated. 

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Author Biographies

Ahmed M. M. El-Saghier, Sohag University, Sohag

Department of Chemistry, Faculty of Science

Mansour A. Makhlouf, Tripoli University, Tripoli

Department of Chemistry, Faculty of Science

Naglaa F. H. Mahmoud, Ain Shams University, Cairo

Department of Chemistry, Faculty of Science

Wedad A. El-Adawish, Al-Zawia University, Al-Zawia

Department of Chemistry, Faculty of Science

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Published

2010-04-10

How to Cite

El-Saghier, A. M. M., Makhlouf, M. A., Mahmoud, N. F. H., & El-Adawish, W. A. (2010). A-Alkenoyl Ketene S,S- and N,S-Acetals As Starting For Unexpected and Novel Synthesis of N-Heterocycles. JOURNAL OF ADVANCES IN CHEMISTRY, 6(1), 861–872. https://doi.org/10.24297/jac.v6i1.965

Issue

Vol. 6 No. 1 (2013)

Section

Articles

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