Effect of Aqueous Extract of Vitis Vinifera l. Leaf on the Rabbit Females Have Highly Thyroxine Induced by Levothyroxine Sodium

Authors

  • Dr. Taghreed Uloom Mohammed Assc. prof .Doctor of the University of Baghdad, College of Education, Ibn al-Haytham College for Pure Sciences
  • Bushra H.Ali Colloge of Education for Pure Science – Ibn- Al-Haitham, Baghdad University, Baghdad
  • Rajaa K.Baker Colloge of Education for Pure Science – Ibn- Al-Haitham, Baghdad University, Baghdad
  • Dheefaf F. Hassan Colloge of Education for Pure Science – Ibn- Al-Haitham, Baghdad University, Baghdad

DOI:

https://doi.org/10.24297/jac.v4i3.944

Keywords:

Vitis Vinifera L., Levo thyroxine sodium, TSH, T3, T4.

Abstract

     L-Thyroxine(T4) and triiodothyronine(T3)are iodine-containing hormones produced from thyroglobulin in the thyroid follicular cells. The stimulation of metabolic rate and regulation of growth and development by these hormones appear to be due to their effects on DNA transcription and, thus, protein synthesis. The aqueous extract of vitis vinifera L. was investigated for its effect on hormones in rabbits. The aqueous extract of plant at a dose level of 50µg/rabbit showed highly significant (p<0.05)on levels of hormones T4, TSH but TSH no significant. L-thyroxine sodium treated group showed a highlysignificant increase in T3 and T4 while there was a highly significant decrease in TSH. From the above results, it is concluded for the first time that aqueous vitvs vinifera L. extract offers significant effect of T3, T4 and TSH in this rabbit females compared with control.

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Author Biographies

Dr. Taghreed Uloom Mohammed, Assc. prof .Doctor of the University of Baghdad, College of Education, Ibn al-Haytham College for Pure Sciences

Department of Chemistry

Bushra H.Ali, Colloge of Education for Pure Science – Ibn- Al-Haitham, Baghdad University, Baghdad

Chemistry department

Rajaa K.Baker, Colloge of Education for Pure Science – Ibn- Al-Haitham, Baghdad University, Baghdad

Chemistry department

Dheefaf F. Hassan, Colloge of Education for Pure Science – Ibn- Al-Haitham, Baghdad University, Baghdad

Chemistry department

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Published

2008-12-12

How to Cite

Mohammed, D. T. U., H.Ali, B., K.Baker, R., & F. Hassan, D. (2008). Effect of Aqueous Extract of Vitis Vinifera l. Leaf on the Rabbit Females Have Highly Thyroxine Induced by Levothyroxine Sodium. JOURNAL OF ADVANCES IN CHEMISTRY, 4(3), 482–487. https://doi.org/10.24297/jac.v4i3.944

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