Synthesis , spectroscopic characterization and biological study of some new Schiff bases based on 2-hydroxybenzadehyde

Authors

  • S. Abdelnabi Department of Chemistry, College of Education for Pure Science, University of Basrah , Basrah ,Iraq
  • Chasib K. Bkhakh Department of Chemistry, College of Education for Pure Science, University of Basrah , Basrah ,Iraq
  • Mouayed Y. Kadhum Department of Chemistry, College of Education for Pure Science, University of Basrah , Basrah ,Iraq

DOI:

https://doi.org/10.24297/jac.v13i12.6117

Keywords:

Schiff base, antibacterial, antifungal, spectroscopic

Abstract

Four new Schiff bases were synthesized from condensation of aldehyde ( 2-hydroxy benzaldehyde ) with aromatic amines (4-introaniline ; 4,4-oxydianiline ; 4,4-diaminodipleny sulfone and sulfanilamide) . These Schiff bases were characterized by IR, NMR , GC. mass and element analysis. Moreover, the Schiff bases were screened for their antibacterial and antifungal activity against various microorganisms and compared with standard compounds. In general , the results were indicated that some Schiff bases had good antimicrobial activity.

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References

[1] P.E. Aranha , M.P. Santos , and E.R. Dockal , polyhedron , 26 , 1373 (2007)
[2] T.M. Ross , S.M. Neville , D.S. Innes , D.R. Turner , B. Moubaraki and K.S. Murray , Dalton Trans. , 39 , 149 (2010)
[3] G. Nocton , P. Horeglad , V. Vetere , J. Pecaut , L. Dubois , P. Maldivi , N.M. Edelstein and M. Mazzanti , J. Am. Chem. Soc. , 132 , 495 (2009)
[4] Z. Cimerman , S. Miljanic and N. Galic , Croatica Chemica Acta , 73 (1) , 81 (2000)
[5] A.Elmali , M. Kabak and Y. Elerman , J. Mol. Struct. , 477 , 151 (2000)
[6] S.N. Pandeya , D. Sriram , G. Nath and E. De Clercq , Pharm. Acta Helv , 74 , 11 (1999)
[7] W.M. Singh and B.C. Dash , Pesticides , 50 , 55 (2000)
[8] J.L. Kelley , J.A. Linn , D.D. Bankston , C.J.Burchall , F.E. Soroko and B.R. Cooper , J. Med. Chem. , 38 , 3676 (1995)
[9] M.T. H. Tarafder , A. Kasbollah , N. Saravanan , K.A. Crouse and A.M. Ali , J. Biochem. Mol. Biol. Biophys. , 6 , 85 (2002)
[10] G.H. Schmid , Organic Chemistry , New York , 1996
[11] C. Spinu and A. Kriza , Acta Chim. Slov. , 47 , 179 (2000)
[12] O. Signorini , E.R. Dockal , G. Castellano and G. Oliva , Polyhedron , 15 , 245 (1995)
[13] J.A. Faniran , K.S. Patel and J.C. Bailar Jr , J. Inorg. Nucl. Chem. , 36 , 1547 (1974)
[14] H.H. Freedman , J. Am. Chem. Soc. , 83 , 2900 (1961)
[15] J.R. Zamian and E.R. Dockal , Transition Met. Chem. , 21 , 370 (1996)
[16] X. Wang , X.M. Zang and H.X. Lin , Polyhedron , 14 , 293 (1993)
[17] G.C. Percy and J. Thomton , J. Inorg. Nucl. Chem. , 35 , 2319 (1973)
[18] E.O. Offiong and S. Martelli , Farmaco , 49 , 513 (1994)
[19] C.S. Allardyce , P.J. Ellis and P.A. Salter , J. Organomet. Chem. , 668 , 35 (2003)
[20] N. Raman , Res. J. Chem. Environ. , 9 , 79 (2005)

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Published

2017-07-11

How to Cite

Abdelnabi, S., Bkhakh, C. K., & Kadhum, M. Y. (2017). Synthesis , spectroscopic characterization and biological study of some new Schiff bases based on 2-hydroxybenzadehyde. JOURNAL OF ADVANCES IN CHEMISTRY, 13(2), 5995–6005. https://doi.org/10.24297/jac.v13i12.6117

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