SYNTHESIS AND NMR SPECTRAL CHARACTERIZATION OF NOVEL 2,3-POLYMETHYLENEPYRIDO[2,3-D]PYRIMIDIN-4-ONES

Abstract

We have synthesized of novel 2,3-polymethylenepyrido[2,3-d]pyrimidin-4-ones via condensation of the 2-aminonicotinic acid together with lactams in the presence of phosphorus oxychloride. The structures of the newly synthesized pyrido[2,3-d]pyrimidines were confirmed by 1H and 13c NMR spectral data.