SYNTHESIS AND CHARACTERIZATION OFGOLDNANOPARTICLESUSING CEFOTAXIMSODIUM AND ITS SCHIFF BASE DERIVATIVE WITH 4-N,N-DIMETHYLAMINO BENSALDEHYDEAS REDUCING ANDSTABILIZING AGENTS

Authors

  • Prof. Dr. Ahlam J. Abdulghani College of Science, Baghdad University, Baghdad
  • Rasha Kudher Hussain College of Science, Baghdad University, Baghdad

DOI:

https://doi.org/10.24297/jac.v11i8.2190

Keywords:

Gold nanoparticles, cefotaxim, Schiff base, AFM, TEM.

Abstract

Conjugated GNPs were synthesized  by one step reaction of AuCl4- with   cefotaxim  (CFX) and its Schiff base derivative with 4-N,N-dimethylamino benzaldehyde [sodium 3-(acetoxymethyl)-7-((2Z)-2-(2-(4-dimethylamino) benzylideneamino) thiazol-4-yl)-2-(methoxyimino) acetamido)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate] (SCFX)without the need of  reducing and functionalizing agents. The reduction process was monitored by uv-visible spectrophotometry  and the synthesized GNPs were characterized by TEM, SEM, AFM and  XRD analysis. The conjugation of GNPs with the two ligands was characterized by FTIR spectrophotometry. The size, morphology, and stability of GNPs were varied with concentration ratio of ligand/Au(III), pH medium and reaction temperature

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Author Biographies

Prof. Dr. Ahlam J. Abdulghani, College of Science, Baghdad University, Baghdad

Chemistry Department

Rasha Kudher Hussain, College of Science, Baghdad University, Baghdad

Chemistry Department

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Published

2015-10-16

How to Cite

J. Abdulghani, P. D. A., & Hussain, R. K. (2015). SYNTHESIS AND CHARACTERIZATION OFGOLDNANOPARTICLESUSING CEFOTAXIMSODIUM AND ITS SCHIFF BASE DERIVATIVE WITH 4-N,N-DIMETHYLAMINO BENSALDEHYDEAS REDUCING ANDSTABILIZING AGENTS. JOURNAL OF ADVANCES IN CHEMISTRY, 11(8), 3838–3849. https://doi.org/10.24297/jac.v11i8.2190

Issue

Vol. 11 No. 8 (2015)

Section

Articles

License

Creative Commons License All articles published in Journal of Advances in Linguistics are licensed under a Creative Commons Attribution 4.0 International License.