STRETCHING PROCESS OF PLASMID DNA MOLECULE IN OPTICAL TWEEZERS USING CW GAUSSIAN LASER BEAM

Authors

  • Quangquy Ho Vietnam Academy of Science and Technology, 18 hoang Quoc Viet, Vietnam
  • Thai Dinh Trung Vinh University, 182 Le Duan, Vinh City
  • Mai Van Luu Vinh University, 182 Le Duan, Vinh City
  • Chu Van Lanh Vinh University, 182 Le Duan, Vinh City
  • Thai Doan Thanh HCM University of Food Industry, 140 Le Trong Tan, Ho Chi Minh City
  • Ho Quang Quy Institute of Applied Physics, VAST, 18 Hoang Quocs Viet, Hanoi

DOI:

https://doi.org/10.24297/jab.v8i1.5312

Keywords:

Laser trapping, Optical devices, Medical and Biotechnology

Abstract

The trapping dynamics of plasmid DNA molecule linking to polystyrene microsphere (trapped bead) in optical tweezers are investigated in the CW regime using the finite difference Langevin equation (FDLE). The obtained results show that, due to the extension of DNA moleucle, the stretching process characterizing by its pulling time, and stretched length depend on the peak intensity of  laser beam and its initial position. The conditions to stretch plasmid DNA molecule in stretching state are discussed and the threshold value of energy of lase beam is found out and compared to that of λ-phage DNA moeucle

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Published

2015-09-25

How to Cite

Ho, Q., Trung, T. D., Luu, M. V., Lanh, C. V., Thanh, T. D., & Quy, H. Q. (2015). STRETCHING PROCESS OF PLASMID DNA MOLECULE IN OPTICAL TWEEZERS USING CW GAUSSIAN LASER BEAM. JOURNAL OF ADVANCES IN BIOLOGY, 8(1), 1456–1461. https://doi.org/10.24297/jab.v8i1.5312

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Articles