TY - JOUR AU - Popova, Prof. Teodora P. PY - 2020/04/19 Y2 - 2024/03/28 TI - Antibacterial Activity of the Original Dietary Supplement Oxidal® in Vitro JF - JOURNAL OF ADVANCES IN AGRICULTURE JA - JAA VL - 11 IS - SE - Articles DO - 10.24297/jaa.v11i.8716 UR - https://rajpub.com/index.php/jaa/article/view/8716 SP - 71-78 AB - <p>Studies have been conducted to determine the antibacterial effect of Oxidal<sup>®</sup> and anolyte against <em>Staphylococcus aureus </em>and<em> Escherichia coli</em>. The bacterial strains tested showed high sensitivity to the dietary supplement Oxidal<sup>®</sup> and to anolyte, as well as to the control antibiotic Thiamphenicol. The mean MPC<sub>50</sub> values of Oxidal<sup>®</sup> for Gram-positive bacteria <em>S. aureus</em> (0.21 ± 0.13 mg/ml) were lower than those for Gram-negative <em>E. coli</em> (0.55 ± 0.24 mg/ml). The dose that fully suppressed <em>S. aureus</em> growth was 0.86 ± 0.52 mg/ml, while for <em>E. coli</em> this dose was significantly higher - 2.40 ± 0.80 mg/ml (P&lt;0.05). For the antibiotic Thiamphenicol, the results were opposite - the mean MPC<sub>50</sub> values for <em>E. coli</em> (2.40 ± 0.80) were lower than those for <em>S. aureus</em> (3.71 ± 2.86). Under the influence of 10% Oxidal<sup>®</sup> solution, the amount of viable <em>S. aureus</em> and <em>E. coli</em> decreased by more than 30% over the untreated control after 20 min. After 45 minutes, only 37% of <em>S. aureus</em> cells and 19% of <em>E. coli</em> cells developed upon cultivation, and after 90 minutes of exposure, about 20% of the cells of the microorganisms understudy of both species remained viable. The fresh anolyte and the one stored for 1 year inactivated <em>S. aureus</em> and <em>E. coli</em> for 2 min in a suspension at a density of 10<sup>6</sup> cells/ml.</p> ER -